{"id":134,"date":"2018-10-01T12:36:09","date_gmt":"2018-10-01T10:36:09","guid":{"rendered":"http:\/\/zfch.home.amu.edu.pl\/?page_id=134"},"modified":"2018-10-01T12:36:09","modified_gmt":"2018-10-01T10:36:09","slug":"dr-marta-ignasiak-kciuk","status":"publish","type":"page","link":"http:\/\/zfch.home.amu.edu.pl\/?page_id=134","title":{"rendered":"Dr. Marta Ignasiak-Kciuk"},"content":{"rendered":"<p style=\"padding-left: 90px;\"><strong>Research Interest:<\/strong><\/p>\n<p style=\"padding-left: 60px;\">1) Protein oxidation induced by light, chemicals and radicals<\/p>\n<p style=\"padding-left: 60px;\">2) Stable modifications and markers of oxidative stress<\/p>\n<p style=\"padding-left: 60px;\">3) Kinetics of biochemical processes<\/p>\n<p style=\"padding-left: 60px;\">4) Fast photochemical reactions induced by aromatic sensitizers \u2013 from transient species to stable products<\/p>\n<p>&nbsp;<\/p>\n<p><u>Grant:<\/u><\/p>\n<ul>\n<li>Two faces of iodide in oxidative stress. Investigation of iodide influence on oxidative stress, Sonata 12, active (2017-2019)<\/li>\n<li>Do sunscreens damage skin proteins? Preludium, NCN, 2011\/03\/N\/ST4\/01290 \u2013 accomplished (2012-14)<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p><strong>PUBLICATIONS:<\/strong><\/p>\n<ol>\n<li>Casaril, A.M., Ignasiak, M.T., Chuang, C.Y., Vieira, B., Padilha, N.B., Carroll, L., Leonardao, E.J., Savegnago, L., Davies, M.J., Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins, <em>Free Radical Biology and Medicine, <\/em>113, 395-405 (2017)<\/li>\n<li>Karimi, M., Ignasiak, M.T., Chan, B., Croft, A.K., Radom, L., Schiesser, C.H., Pattison, D.I., Davies, M.J., Reactivity of disulfide bonds is markedly affected by structure and environment: Implications for protein modification and stability, <em>Scientific Reports, 6, 38572 <\/em>(2016)<\/li>\n<li>Storkey, C., Pattison, D.I., Ignasiak, M.T., Schiesser, C.H., Davies, M.J., Kinetic of reaction of peroxynitrite with selenium- and sulfur-containing compounds: Absolute rate constants and assessment of biological significance, <em>Free Radical Biology and Medicine, <\/em>89, 1049-1056 (2015)<\/li>\n<li>Scuderi, D., Ignasiak, M.T., Serfaty, X., De Oliveira, P., Houee-Levin, C., Tandem mass spectrometry and infrared spectroscopy as tool to identify peptide oxidized residues, <em>Physical Chemistry Chemical Physics, <\/em>17 (39) 25998-26007, 2015<\/li>\n<li>Ignasiak, M.T., Houee-Levin, C., Kciuk, G., Marciniak, B., Pedzinski, T., A reevaluation of the photolytic properties of 2-hydroxybenzophenone-based UV sunscreens: Are chemical sunscreens inoffensive? <em>ChemPhysChem, 16 (3) 628-633, 2015<\/em><\/li>\n<li>Pedzinski, T., Bobrowski, K., Ignasiak, M., Kciuk, G., Hug, G.L., Lewandowska-Andraloic, A., Marciniak, B., 3-Carboxybenzophenone (3-CB) as an efficient sensitizer in the photooxidation of methionyl-leucine in aqueous solutions: Spectral, kinetic and acid-base properties of 3-CB derived transients, <em>Journal of Photochemistry and Photobiology A: Chemistry, 287, 1-7, 2014<\/em><\/li>\n<li>Ignasiak, M., Pedzinski, T., Rusconi, F., Filipiak, P., Bobrowski, K., Houee-Levin, C., Marciniak, B., Photosensitized oxidation of methionine-containing dipeptides. From the transients to the final products, <em>Journal of Physical Chemistry B, 118 (29), 8549-8558, 2014<\/em><\/li>\n<li>Ignasiak, M., Marciniak, B., Houee-Levin, C., A long story of sensitized one-electron photo-oxidation of methionine (Review), <em>Israel Journal of Chemistry, 54 (3) 248-253, 2014<\/em><\/li>\n<li>Ignasiak, M., De Oliveira, P., Houee-Levin, C., Scuderi, D., Oxidation of methionine-containing peptides by \u00b7OH radicals: Is sulfoxide the only product? Study by mass spectrometry and IRMPD spectroscopy, <em>Chemical Physics Letters, 590, 35-40, 2013<\/em><\/li>\n<li>Ignasiak, M., Scuderi, D., De Oliveira, P., Pedzinski, T., Rayah, Y., Houee-Levin, C., Characterization by mass spectrometry and IRMPD spectroscopy of the sulfoxide group in oxidized methionine and related compounds, <em>Chemical Physics Letters, 502 (1-3), 29-36, 2011<\/em><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Research Interest: 1) Protein oxidation induced by light, chemicals and radicals 2) Stable modifications and markers of oxidative stress 3) Kinetics of biochemical processes 4) Fast photochemical reactions induced by &#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"http:\/\/zfch.home.amu.edu.pl\/index.php?rest_route=\/wp\/v2\/pages\/134"}],"collection":[{"href":"http:\/\/zfch.home.amu.edu.pl\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/zfch.home.amu.edu.pl\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/zfch.home.amu.edu.pl\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/zfch.home.amu.edu.pl\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=134"}],"version-history":[{"count":2,"href":"http:\/\/zfch.home.amu.edu.pl\/index.php?rest_route=\/wp\/v2\/pages\/134\/revisions"}],"predecessor-version":[{"id":706,"href":"http:\/\/zfch.home.amu.edu.pl\/index.php?rest_route=\/wp\/v2\/pages\/134\/revisions\/706"}],"wp:attachment":[{"href":"http:\/\/zfch.home.amu.edu.pl\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=134"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}